Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS28290

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest
Locus Tag
BURCENK562V_RS28290
NCBI Old Locus TagBURCENK562V_C6659
Name
Synonym: bcsA
Replicon ctg7180000002941
Genomic location 462214 - 463059 (- strand)
CommentPart of the T6SS gene cluster

Cross-References

RefSeq WP_006488977.1
GI 493535018
GI 493535018
NCBI Locus Tag BURCENK562V_RS28290
NCBI Old Locus Tag BURCENK562V_C6659
RefSeq WP_006488977.1

Product

Feature Type CDS
Coding Frame 1
Product Name
serine-type D-Ala-D-Ala carboxypeptidase domain protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 10.44
Kyte-Doolittle Hydrophobicity Value -0.109
Molecular Weight (kDa) 31344.0
Isoelectric Point (pI) 10.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000379 (642 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:

Human Homologs

References

A novel sensor kinase-response regulator hybrid controls biofilm formation and type VI secretion system activity in Burkholderia cenocepacia.
Aubert DF, Flannagan RS, Valvano MA
Infect Immun 2008 May;76(5):1979-91
PubMed ID: 18316384
Anchoring the type VI secretion system to the peptidoglycan: TssL, TagL, TagP... what else?
Aschtgen MS, Thomas MS, Cascales E
Virulence 2010 Nov-Dec;1(6):535-40
PubMed ID: 21178498
Quantification of type VI secretion system activity in macrophages infected with Burkholderia cenocepacia.
Aubert DF, Hu S, Valvano MA
Microbiology 2015 Nov;161(11):2161-73
PubMed ID: 26364149