Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS29130 (galE)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest |
| Locus Tag |
BURCENK562V_RS29130
|
| NCBI Old Locus Tag | BURCENK562V_C5757 |
| Name |
galE
|
| Replicon | ctg7180000002940C |
| Genomic location | 116260 - 117282 (- strand) |
| Comment | Belongs to the O antigen biosynthesis gene cluster |
Cross-References
| RefSeq | WP_006485111.1 |
| GI | 493531108 |
| EC Number | 5.1.3.2 |
| GI | 493531108 |
| NCBI Locus Tag | BURCENK562V_RS29130 |
| NCBI Old Locus Tag | BURCENK562V_C5757 |
| RefSeq | WP_006485111.1 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
UDP-glucose 4-epimerase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -5.16 |
| Kyte-Doolittle Hydrophobicity Value | -0.070 |
| Molecular Weight (kDa) | 36862.6 |
| Isoelectric Point (pI) | 5.88 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG000745 (653 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BURCENK562V_RS29130
Search term: galE
Search term: UDP-glucose 4-epimerase
|
Human Homologs
|
Ensembl
97, assembly
GRCh38.p12
|
UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116]
E-value:
4.9e-116
Percent Identity:
57.4
|
|
Ensembl
97, assembly
GRCh38.p12
|
UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116]
E-value:
4.9e-116
Percent Identity:
57.4
|
References
|
Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis.
Ortega X, Hunt TA, Loutet S, Vinion-Dubiel AD, Datta A, Choudhury B, Goldberg JB, Carlson R, Valvano MA
J Bacteriol 2005 Feb;187(4):1324-33
PubMed ID: 15687196
|