Burkholderia cenocepacia AU 1054, BCEN_RS12460

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia AU 1054
GCF_000014085.1|latest
Locus Tag
BCEN_RS12460
NCBI Old Locus TagBcen_2504
Name
Replicon chromosome 1
Genomic location 2749599 - 2750231 (- strand)

Cross-References

RefSeq WP_011546480.1
GI 499865746
NCBI Locus Tag BCEN_RS12460
NCBI Old Locus Tag Bcen_2504
RefSeq WP_011546480.1

Product

Feature Type CDS
Coding Frame NA
Product Name
7-carboxy-7-deazaguanine synthase
Synonyms
Evidence for Translation
Charge (pH 7) -8.49
Kyte-Doolittle Hydrophobicity Value -0.168
Molecular Weight (kDa) 23198.2
Isoelectric Point (pI) 4.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4NJK LYASE 11/10/13 Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 7-carboxy-7-deazaguanine, and Mg2+ BURKHOLDERIA MULTIVORANS 1.911 X-RAY DIFFRACTION 97.1
4NJJ LYASE 11/10/13 Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 6-carboxy-5,6,7,8-tetrahydropterin, and Manganese(II) BURKHOLDERIA MULTIVORANS 2.7 X-RAY DIFFRACTION 97.1
4NJH LYASE 11/10/13 Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet and 6-carboxy-5,6,7,8-tetrahydropterin BURKHOLDERIA MULTIVORANS 1.898 X-RAY DIFFRACTION 97.1
4NJG LYASE 11/10/13 Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet and 6-carboxypterin BURKHOLDERIA MULTIVORANS 2.598 X-RAY DIFFRACTION 97.1
4NJI LYASE 11/10/13 Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 6-carboxy-5,6,7,8-tetrahydropterin, and Mg2+ BURKHOLDERIA MULTIVORANS 2.197 X-RAY DIFFRACTION 97.1

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002946 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCEN_RS12460

Human Homologs

References

No references are associated with this feature.