Burkholderia cenocepacia J2315, BCAS0733

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAS0733
NCBI Locus Tag	QU43_RS72305
Name
Replicon	chromosome 3
Genomic location	805991 - 807307 (- strand)

Cross-References

RefSeq	WP_006485645.1
GI	197295563
Entrez	6804052
GI	197295563
INSDC	CAR57667.1
NCBI Locus Tag	QU43_RS72305
NCBI Old Locus Tag	BCAS0733
RefSeq	WP_006485645.1,GeneID
UniParc	UPI00017BB296
UniProtKB Acc	B4EPC1
UniProtKB ID	B4EPC1_BURCJ
UniRef100	UniRef100_A0A0D1DGQ7
UniRef50	UniRef50_G8QBC2
UniRef90	UniRef90_Q39PB0

Product

Feature Type	CDS
Coding Frame	1
Product Name	dihydropyrimidine dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	-9.04
Kyte-Doolittle Hydrophobicity Value	-0.117
Molecular Weight (kDa)	47259.5
Isoelectric Point (pI)	5.43

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 363 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG005135 (307 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAS0733 Search term: dihydropyrimidine dehydrogenase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000359211 dihydropyrimidine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3012] E-value: 3.6e-71 Percent Identity: 34.0

References