Burkholderia cenocepacia J2315, BCAS0607 (hbD)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAS0607
NCBI Locus Tag	QU43_RS71690
Name	hbD
Replicon	chromosome 3
Genomic location	663639 - 664493 (- strand)

Cross-References

RefSeq	WP_006489742.1
GI	197295448
Entrez	6804431
GI	197295448
INSDC	CAR57539.1
NCBI Locus Tag	QU43_RS71690
NCBI Old Locus Tag	BCAS0607
RefSeq	WP_006489742.1,GeneID
UniParc	UPI00017BB069
UniProtKB Acc	B4EP01
UniProtKB ID	B4EP01_BURCJ
UniRef100	UniRef100_B4EP01
UniRef50	UniRef50_A9ATI7
UniRef90	UniRef90_A9ATI7

Product

Feature Type	CDS
Coding Frame	1
Product Name	3-hydroxybutyryl-CoA dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	-2.58
Kyte-Doolittle Hydrophobicity Value	0.343
Molecular Weight (kDa)	29773.2
Isoelectric Point (pI)	5.42

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 443 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG005017 (294 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAS0607 Search term: hbD Search term: 3-hydroxybutyryl-CoA dehydrogenase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000312288 hydroxyacyl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4799] E-value: 7.4e-49 Percent Identity: 39.0

References