Burkholderia cenocepacia J2315, BCAL3439 (proB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL3439
NCBI Locus TagQU43_RS53895
Name
proB
Replicon chromosome 1
Genomic location 3766619 - 3767737 (- strand)

Cross-References

RefSeq WP_006476997.1
GI 206561776
Entrez 6933218
GI 206561776
INSDC CAR53762.1
NCBI Locus Tag QU43_RS53895
NCBI Old Locus Tag BCAL3439
RefSeq WP_006476997.1,GeneID
UniParc UPI000052E818
UniProtKB Acc B4E5W9
UniProtKB ID PROB_BURCJ
UniRef100 UniRef100_Q1BZD9
UniRef50 UniRef50_Q3K6L0
UniRef90 UniRef90_Q2SZF9

Product

Feature Type CDS
Coding Frame 1
Product Name
gamma-glutamyl kinase
Synonyms
Evidence for Translation
Charge (pH 7) -0.09
Kyte-Doolittle Hydrophobicity Value 0.062
Molecular Weight (kDa) 39211.6
Isoelectric Point (pI) 6.98

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4Q1T TRANSFERASE 04/04/14 Crystal structure of a glutamate 5-kinase from Burkholderia thailandensis BURKHOLDERIA THAILANDENSIS 2.15 X-RAY DIFFRACTION 93.3

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 524 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000472 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL3439
Search term: proB

Human Homologs

Ensembl 97, assembly GRCh38.p12
aldehyde dehydrogenase 18 family member A1 [Source:HGNC Symbol;Acc:HGNC:9722]
E-value: 1.3e-32
Percent Identity: 32.0
Ensembl 97, assembly GRCh38.p12
aldehyde dehydrogenase 18 family member A1 [Source:HGNC Symbol;Acc:HGNC:9722]
E-value: 1.3e-32
Percent Identity: 32.2

References

No references are associated with this feature.