Burkholderia cenocepacia J2315, BCAL3389 (tktA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL3389
NCBI Locus TagQU43_RS53645
Name
tktA
Replicon chromosome 1
Genomic location 3713341 - 3715413 (- strand)

Cross-References

RefSeq WP_006485709.1
GI 206561726
Entrez 6933619
GI 206561726
INSDC CAR53712.1
NCBI Locus Tag QU43_RS53645
NCBI Old Locus Tag BCAL3389
RefSeq WP_006485709.1,GeneID
UniParc UPI000052ECDB
UniProtKB Acc B4EEX7
UniProtKB ID B4EEX7_BURCJ
UniRef100 UniRef100_B1JVF3
UniRef50 UniRef50_A1WEC7
UniRef90 UniRef90_Q2SZA7

Product

Feature Type CDS
Coding Frame 1
Product Name
transketolase
Synonyms
Evidence for Translation
Charge (pH 7) -11.86
Kyte-Doolittle Hydrophobicity Value -0.117
Molecular Weight (kDa) 74199.4
Isoelectric Point (pI) 6.19

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3UK1 TRANSFERASE 11/08/11 Crystal structure of a transketolase from Burkholderia thailandensis with an oxidized cysteinesulfonic acid in the active site BURKHOLDERIA THAILANDENSIS 2.15 X-RAY DIFFRACTION 92.5
3UPT TRANSFERASE 11/18/11 Crystal structure of a transketolase from Burkholderia pseudomallei bound to TPP, calcium and ribose-5-phosphate BURKHOLDERIA THAILANDENSIS 2.4 X-RAY DIFFRACTION 92.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 610 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000522 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL3389
Search term: tktA
Search term: transketolase

Human Homologs

References

No references are associated with this feature.