Burkholderia cenocepacia J2315, BCAL1205

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL1205
NCBI Locus TagQU43_RS42525
Name
Replicon chromosome 1
Genomic location 1315386 - 1316372 (- strand)

Cross-References

RefSeq WP_006481801.1
GI 206559583
Entrez 6931544
GI 206559583
INSDC CAR51508.1
NCBI Locus Tag QU43_RS42525
NCBI Old Locus Tag BCAL1205
RefSeq WP_006481801.1,GeneID
UniParc UPI00017B93B2
UniProtKB Acc B4EEE3
UniProtKB ID B4EEE3_BURCJ
UniRef100 UniRef100_B4EEE3
UniRef50 UniRef50_H3RCX2
UniRef90 UniRef90_A0K662

Product

Feature Type CDS
Coding Frame 1
Product Name
short chain dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) 5.16
Kyte-Doolittle Hydrophobicity Value -0.067
Molecular Weight (kDa) 34170.5
Isoelectric Point (pI) 9.48

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5JYD OXIDOREDUCTASE 05/13/16 Crystal Structure of a Putative Short Chain Dehydrogenase from Burkholderia cenocepacia BURKHOLDERIA CENOCEPACIA (STRAIN ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) 1.65 X-RAY DIFFRACTION 100.0
5U8P OXIDOREDUCTASE 12/14/16 Crystal structure of a short chain dehydrogenase from Burkholderia cenocepacia J2315 in complex with NAD BURKHOLDERIA CENOCEPACIA (STRAIN ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) 1.4 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 650 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006054 (53 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL1205

Human Homologs

Ensembl 97, assembly GRCh38.p12
3-hydroxybutyrate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:32389]
E-value: 2.3e-17
Percent Identity: 32.8

References

No references are associated with this feature.