Burkholderia cenocepacia J2315, BCAL1010 (nagZ2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL1010
NCBI Locus TagQU43_RS41615
Name
nagZ2
Replicon chromosome 1
Genomic location 1096806 - 1097834 (+ strand)

Cross-References

RefSeq WP_006485604.1
GI 206559403
Entrez 6933288
GI 206559403
NCBI Locus Tag QU43_RS41615
NCBI Old Locus Tag BCAL1010
RefSeq WP_006485604.1,GeneID
UniProtKB Acc B4EA43
UniProtKB ID B4EA43_BURCJ

Product

Feature Type CDS
Coding Frame 1
Product Name
beta-hexosaminidase
Synonyms
Evidence for Translation
Charge (pH 7) 3.29
Kyte-Doolittle Hydrophobicity Value 0.019
Molecular Weight (kDa) 37035.2
Isoelectric Point (pI) 8.03

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4MSS HYDROLASE/HYDROLASE INHIBITOR 09/18/13 Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to (3S,4R,5R,6S)-3-acetamido-4,5,6-trihydroxyazepane BURKHOLDERIA CENOCEPACIA 1.8 X-RAY DIFFRACTION 100.0
6DTE HYDROLASE 06/15/18 GlcNAc-inspired cyclophellitol bound to NagZ BURKHOLDERIA CENOCEPACIA 1.929 X-RAY DIFFRACTION 100.0
4GNV HYDROLASE 08/17/12 Crystal structure of beta-hexosaminidase 1 from Burkholderia cenocepacia J2315 with bound N-Acetyl-D-Glucosamine BURKHOLDERIA CENOCEPACIA 1.5 X-RAY DIFFRACTION 100.0
5UTP HYDROLASE/HYDROLASE INHIBITOR 02/15/17 Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to N-ethylbutyryl-PUGNAc BURKHOLDERIA CENOCEPACIA 2.2 X-RAY DIFFRACTION 100.0
5UTR HYDROLASE/HYDROLASE INHIBITOR 02/15/17 Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to (3S,4R,5R,6S)-3-butyryl-4,5,6-trihydroxyazepane BURKHOLDERIA CENOCEPACIA 2.15 X-RAY DIFFRACTION 100.0
5UTQ HYDROLASE/HYDROLASE INHIBITOR 02/15/17 Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to PUGNAc BURKHOLDERIA CENOCEPACIA 2.2 X-RAY DIFFRACTION 100.0
4G6C HYDROLASE 07/18/12 Crystal structure of beta-hexosaminidase 1 from Burkholderia cenocepacia J2315 BURKHOLDERIA CENOCEPACIA 1.38 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 468 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000980 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL1010
Search term: nagZ2

Human Homologs

References

No references are associated with this feature.