Burkholderia cenocepacia J2315, BCAL0670

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL0670
NCBI Locus Tag	QU43_RS39910
Name
Replicon	chromosome 1
Genomic location	728316 - 728993 (- strand)

Cross-References

RefSeq	WP_006487603.1
GI	206559068
Entrez	6931125
GI	206559068
INSDC	CAR50979.1
NCBI Locus Tag	QU43_RS39910
NCBI Old Locus Tag	BCAL0670
RefSeq	WP_006487603.1,GeneID
UniParc	UPI00017B9150
UniProtKB Acc	B4E9M0
UniProtKB ID	B4E9M0_BURCJ
UniRef100	UniRef100_A0A0D1D851
UniRef50	UniRef50_A9AE50
UniRef90	UniRef90_A9AE50

Product

Feature Type	CDS
Coding Frame	1
Product Name	short chain dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	-2.07
Kyte-Doolittle Hydrophobicity Value	0.010
Molecular Weight (kDa)	24098.1
Isoelectric Point (pI)	6.12

Subcellular localization

Individual Mappings	Localization Confidence PMID Extracellular Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
5U1P	OXIDOREDUCTASE	11/28/16	Crystal structure of NADP-dependent carbonyl reductase from Burkholderia multivorans in complex with NADP	BURKHOLDERIA MULTIVORANS (STRAIN ATCC 17616 / 249)	1.9	X-RAY DIFFRACTION	90.9
5TQV	OXIDOREDUCTASE	10/24/16	Crystal structure of NADP-dependent carbonyl reductase from Burkholderia multivorans	BURKHOLDERIA MULTIVORANS (STRAIN ATCC 17616 / 249)	1.65	X-RAY DIFFRACTION	90.9
5IDW	OXIDOREDUCTASE	02/24/16	Crystal structure of an oxidoreductase from Burkholderia vietnamiensis in complex with NADP	BURKHOLDERIA VIETNAMIENSIS (STRAIN G4 / LMG 22486)	2.0	X-RAY DIFFRACTION	92.7
5IDQ	OXIDOREDUCTASE	02/24/16	Crystal structure of a Short-chain dehydrogenase/reductase (SDR)from Burkholderia vietnamiensis at 1.55 A resolution	BURKHOLDERIA VIETNAMIENSIS (STRAIN G4 / LMG 22486)	1.55	X-RAY DIFFRACTION	92.7

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 484 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002768 (650 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL0670 Search term: short chain dehydrogenase

Human Homologs

References