Burkholderia cenocepacia J2315, BCAL0345 (tssF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0345
NCBI Locus TagQU43_RS38260
Name
tssF
Synonym: bcsH
Replicon chromosome 1
Genomic location 370125 - 371960 (+ strand)
CommentPart of the T6SS gene cluster

Cross-References

RefSeq WP_006484396.1
GI 206558751
Entrez 6930890
GI 206558751
INSDC CAR50655.1
NCBI Locus Tag QU43_RS38260
NCBI Old Locus Tag BCAL0345
RefSeq WP_006484396.1,GeneID
UniParc UPI00017B9100
UniProtKB Acc B4E6R7
UniProtKB ID B4E6R7_BURCJ
UniRef100 UniRef100_A0A0D1C278
UniRef50 UniRef50_C4AZ32
UniRef90 UniRef90_J4RM29

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion system protein TssF
Product Name Confidence: Class 1
Synonyms putative type VI secretion system protein TssF
Evidence for Translation
Charge (pH 7) -0.16
Kyte-Doolittle Hydrophobicity Value -0.081
Molecular Weight (kDa) 68840.0
Isoelectric Point (pI) 6.98

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 106 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000370 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0345
Search term: tssF

Human Homologs

References

A novel sensor kinase-response regulator hybrid controls biofilm formation and type VI secretion system activity in Burkholderia cenocepacia.
Aubert DF, Flannagan RS, Valvano MA
Infect Immun 2008 May;76(5):1979-91
PubMed ID: 18316384
Quantification of type VI secretion system activity in macrophages infected with Burkholderia cenocepacia.
Aubert DF, Hu S, Valvano MA
Microbiology 2015 Nov;161(11):2161-73
PubMed ID: 26364149