Burkholderia cenocepacia J2315, BCAS0366

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0050661 NADP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019632 shikimate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004764 shikimate 3-dehydrogenase (NADP+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc chorismate biosynthesis from 3-dehydroquinate InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01230 Biosynthesis of amino acids 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00400 Phenylalanine, tyrosine and tryptophan biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00400 Phenylalanine, tyrosine and tryptophan biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF18317 Shikimate 5'-dehydrogenase C-terminal domain IPR041121 SDH, C-terminal 243 270 7.3E-10
Pfam PF01488 Shikimate / quinate 5-dehydrogenase IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase 121 197 1.5E-7
Gene3D G3DSA:3.40.50.10860 6 260 1.2E-70
Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. IPR022893 Shikimate dehydrogenase family 2 275 29.192
Gene3D G3DSA:3.40.50.720 119 242 1.2E-70
TIGRFAM TIGR00507 aroE: shikimate dehydrogenase IPR011342 Shikimate dehydrogenase 4 272 4.5E-71
CDD cd01065 NAD_bind_Shikimate_DH 105 260 7.56521E-26
SUPERFAMILY SSF53223 2 103 2.3E-25
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 105 271 1.61E-39
Pfam PF08501 Shikimate dehydrogenase substrate binding domain IPR013708 Shikimate dehydrogenase substrate binding, N-terminal 7 91 3.5E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.