Burkholderia cenocepacia J2315, BCAM2194 (mmsA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004491 methylmalonate-semialdehyde dehydrogenase (acylating) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd07085
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.309.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd07085
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.309.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004491 methylmalonate-semialdehyde dehydrogenase (acylating) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd07085
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd07085
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00171
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00171
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc 2,4-dinitrotoluene degradation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00410 beta-Alanine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00640 Propanoate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00280 Valine, leucine and isoleucine degradation 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj00640 Propanoate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00280 Valine, leucine and isoleucine degradation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00562 Inositol phosphate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01200 Carbon metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00171 Aldehyde dehydrogenase family IPR015590 Aldehyde dehydrogenase domain 24 488 3.0E-140
ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. IPR016160 Aldehyde dehydrogenase, cysteine active site 286 297 -
Gene3D G3DSA:3.40.309.10 IPR016163 Aldehyde dehydrogenase, C-terminal 261 461 1.1E-145
TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) IPR010061 Methylmalonate-semialdehyde dehydrogenase 16 492 7.3E-228
SUPERFAMILY SSF53720 IPR016161 Aldehyde/histidinol dehydrogenase 12 495 2.36E-147
CDD cd07085 ALDH_F6_MMSDH IPR010061 Methylmalonate-semialdehyde dehydrogenase 16 492 0.0
Gene3D G3DSA:3.40.605.10 IPR016162 Aldehyde dehydrogenase, N-terminal 36 469 1.1E-145

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.