Burkholderia cenocepacia J2315, BCAL2946 (udg)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003979 UDP-glucose 6-dehydrogenase activity
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
Biological Process GO:0009244 lipopolysaccharide core region biosynthetic process
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00984
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003979 UDP-glucose 6-dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF500134
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00984
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000271 polysaccharide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF500134
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00984
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc teichuronic acid biosynthesis (<i>B. subtilis</i> 168) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00500 Starch and sucrose metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00520 Amino sugar and nucleotide sugar metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00053 Ascorbate and aldarate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00053 Ascorbate and aldarate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00520 Amino sugar and nucleotide sugar metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UDP-&alpha;-D-glucuronate biosynthesis (from UDP-glucose) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00040 Pentose and glucuronate interconversions 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00040 Pentose and glucuronate interconversions InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF48179 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 212 309 3.97E-33
TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase IPR017476 UDP-glucose/GDP-mannose dehydrogenase 1 436 1.4E-132
SMART SM00984 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal 328 440 5.6E-49
PIRSF PIRSF500134 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type 1 458 2.1E-187
SUPERFAMILY SSF52413 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily 314 451 5.62E-40
Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal 1 189 1.3E-63
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 1 202 8.14E-53
PIRSF PIRSF000124 IPR017476 UDP-glucose/GDP-mannose dehydrogenase 1 455 4.5E-149
Gene3D G3DSA:3.40.50.720 1 210 2.6E-84
Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation 212 304 2.2E-37
Gene3D G3DSA:1.20.5.100 211 242 4.6E-18
ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile. 1 18 5.0
Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal 328 439 5.8E-32
Gene3D G3DSA:3.40.50.720 243 465 2.5E-84

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.