Burkholderia cenocepacia J2315, BCAL0226 (rpoB)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0032549	ribonucleoside binding	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00653	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003677	DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PS01166	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:G3DSA:2.40.50.150	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006351	transcription, DNA-templated	ISM Inferred from Sequence Model Term mapped from: InterPro:PS01166	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	bcj00230	Purine metabolism	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj00240	Pyrimidine metabolism	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01100	Metabolic pathways	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj03020	RNA polymerase	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Gene3D	G3DSA:2.40.50.100				720	794	1.7E-29
ProSitePatterns	PS01166	RNA polymerases beta chain signature.	IPR007121	RNA polymerase, beta subunit, conserved site	1082	1094	-
Pfam	PF04565	RNA polymerase Rpb2, domain 3	IPR007645	RNA polymerase Rpb2, domain 3	519	586	4.8E-32
Pfam	PF00562	RNA polymerase Rpb2, domain 6	IPR007120	DNA-directed RNA polymerase, subunit 2, hybrid-binding domain	726	1290	1.2E-156
TIGRFAM	TIGR02013	rpoB: DNA-directed RNA polymerase, beta subunit	IPR010243	DNA-directed RNA polymerase beta subunit, bacterial-type	8	1364	0.0
Pfam	PF10385	RNA polymerase beta subunit external 1 domain	IPR019462	DNA-directed RNA polymerase, beta subunit, external 1 domain	597	662	2.4E-24
Gene3D	G3DSA:3.90.1100.10				448	636	7.5E-73
Gene3D	G3DSA:3.90.1100.10				18	176	4.5E-49
Pfam	PF04561	RNA polymerase Rpb2, domain 2	IPR007642	RNA polymerase Rpb2, domain 2	360	460	8.2E-14
Hamap	MF_01321	DNA-directed RNA polymerase subunit beta [rpoB].	IPR010243	DNA-directed RNA polymerase beta subunit, bacterial-type	13	1368	12.2
Pfam	PF04561	RNA polymerase Rpb2, domain 2	IPR007642	RNA polymerase Rpb2, domain 2	156	228	8.3E-7
Pfam	PF04563	RNA polymerase beta subunit	IPR007644	RNA polymerase, beta subunit, protrusion	27	506	2.2E-35
Gene3D	G3DSA:2.40.50.150		IPR014724	RNA polymerase Rpb2, OB-fold	839	956	4.6E-44
Pfam	PF04560	RNA polymerase Rpb2, domain 7	IPR007641	RNA polymerase Rpb2, domain 7	1292	1366	1.5E-25
Gene3D	G3DSA:3.90.1100.10				649	719	6.2E-21
Gene3D	G3DSA:2.40.270.10		IPR037033	DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily	796	838	1.2E-6
Gene3D	G3DSA:2.40.270.10		IPR037033	DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily	1054	1268	1.2E-81
CDD	cd00653	RNA_pol_B_RPB2	IPR015712	DNA-directed RNA polymerase, subunit 2	27	1366	0.0
SUPERFAMILY	SSF64484				11	1366	0.0
Gene3D	G3DSA:3.90.1110.10		IPR037034	RNA polymerase Rpb2, domain 2 superfamily	323	447	5.6E-31
Gene3D	G3DSA:3.90.1800.10				1278	1331	5.0E-11

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.