Burkholderia cenocepacia J2315, BCAL0040 (hemE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0040
NCBI Locus TagQU43_RS36690
Name
hemE
Replicon chromosome 1
Genomic location 44321 - 45415 (+ strand)

Cross-References

RefSeq YP_002229204.1
GI 206558444
Entrez 6933957
GI 206558444
INSDC CAR50346.1
NCBI Locus Tag QU43_RS36690
NCBI Old Locus Tag BCAL0040
RefSeq YP_002229204.1
UniParc UPI00017B9124
UniProtKB Acc B4EEZ3
UniProtKB ID DCUP_BURCJ
UniRef100 UniRef100_B4EEZ3
UniRef50 UniRef50_Q5ZTY0
UniRef90 UniRef90_A4JA40

Product

Feature Type CDS
Coding Frame 1
Product Name
uroporphyrinogen decarboxylase
Synonyms
Evidence for Translation
Charge (pH 7) -5.62
Kyte-Doolittle Hydrophobicity Value -0.071
Molecular Weight (kDa) 39544.5
Isoelectric Point (pI) 6.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4EXQ BIOSYNTHETIC PROTEIN 04/30/12 CRYSTAL STRUCTURE of UROPORPHYRINOGEN DECARBOXYLASE (UPD) FROM BURKHOLDERIA THAILANDENSIS E264 BURKHOLDERIA THAILANDENSIS 1.65 X-RAY DIFFRACTION 93.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 475 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000096 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0040
Search term: hemE

Human Homologs

Ensembl 86, assembly GRCh38.p7
uroporphyrinogen decarboxylase [Source:HGNC Symbol;Acc:HGNC:12591]
E-value: 4.7e-87
Percent Identity: 47.6

References

No references are associated with this feature.