Burkholderia cenocepacia J2315, BCAL0040 (hemE)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0006779 | porphyrin-containing compound biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01464
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004853 | uroporphyrinogen decarboxylase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01464
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| MetaCyc | 3,8-divinyl-chlorophyllide <i>a</i> biosynthesis III (aerobic, light independent) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bcj00860 | Porphyrin and chlorophyll metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | 3,8-divinyl-chlorophyllide <i>a</i> biosynthesis II (anaerobic) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bcj01110 | Biosynthesis of secondary metabolites | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | heme <i>b</i> biosynthesis IV (Gram-positive bacteria) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00860 | Porphyrin and chlorophyll metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bcj01100 | Metabolic pathways | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| TIGRFAM | TIGR01464 | hemE: uroporphyrinogen decarboxylase | IPR006361 | Uroporphyrinogen decarboxylase HemE | 10 | 352 | 1.1E-124 |
| Pfam | PF01208 | Uroporphyrinogen decarboxylase (URO-D) | IPR000257 | Uroporphyrinogen decarboxylase (URO-D) | 7 | 353 | 1.1E-130 |
| Gene3D | G3DSA:3.20.20.210 | IPR038071 | UROD/MetE-like superfamily | 1 | 364 | 1.9E-161 | |
| CDD | cd00717 | URO-D | IPR006361 | Uroporphyrinogen decarboxylase HemE | 11 | 352 | 0.0 |
| ProSitePatterns | PS00907 | Uroporphyrinogen decarboxylase signature 2. | IPR000257 | Uroporphyrinogen decarboxylase (URO-D) | 148 | 164 | - |
| ProSitePatterns | PS00906 | Uroporphyrinogen decarboxylase signature 1. | IPR000257 | Uroporphyrinogen decarboxylase (URO-D) | 23 | 32 | - |
| Hamap | MF_00218 | Uroporphyrinogen decarboxylase [hemE]. | IPR006361 | Uroporphyrinogen decarboxylase HemE | 7 | 355 | 49.816 |
| SUPERFAMILY | SSF51726 | IPR038071 | UROD/MetE-like superfamily | 5 | 356 | 6.8E-113 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.