Burkholderia cenocepacia J2315, BCAL0010 (phhA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009072 aromatic amino acid family metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.800.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005506 iron ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.800.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006559 L-phenylalanine catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01267
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004497 monooxygenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.800.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004505 phenylalanine 4-monooxygenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01267
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS51410
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS51410
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00790 Folate biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-tyrosine biosynthesis IV InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00360 Phenylalanine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01230 Biosynthesis of amino acids 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc L-phenylalanine degradation V InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00400 Phenylalanine, tyrosine and tryptophan biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00400 Phenylalanine, tyrosine and tryptophan biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj00360 Phenylalanine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
ProSiteProfiles PS51410 Biopterin-dependent aromatic amino acid hydroxylase family profile. IPR019774 Aromatic amino acid hydroxylase, C-terminal 1 297 103.106
PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature IPR019774 Aromatic amino acid hydroxylase, C-terminal 151 170 4.9E-13
PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature IPR019774 Aromatic amino acid hydroxylase, C-terminal 228 247 4.9E-13
TIGRFAM TIGR01267 Phe4hydrox_mono: phenylalanine-4-hydroxylase IPR005960 Phenylalanine-4-hydroxylase, monomeric form 22 268 7.7E-107
ProSitePatterns PS00367 Biopterin-dependent aromatic amino acid hydroxylases signature. IPR018301 Aromatic amino acid hydroxylase, iron/copper binding site 130 141 -
SUPERFAMILY SSF56534 IPR036329 Aromatic amino acid monoxygenase, C-terminal domain superfamily 10 292 2.62E-100
CDD cd03348 pro_PheOH IPR005960 Phenylalanine-4-hydroxylase, monomeric form 22 252 3.478E-132
PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature IPR019774 Aromatic amino acid hydroxylase, C-terminal 87 109 4.9E-13
PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature IPR019774 Aromatic amino acid hydroxylase, C-terminal 196 214 4.9E-13
Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase IPR019774 Aromatic amino acid hydroxylase, C-terminal 32 249 1.7E-46
Gene3D G3DSA:1.10.800.10 IPR036951 Aromatic amino acid hydroxylase superfamily 2 297 7.9E-106

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.