Burkholderia pseudomallei 1710b, BURPS1710b_A0569 (bprA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 1710b
GCF_000012785.1|latest
Locus Tag
BURPS1710b_A0569
NCBI Locus TagBURPS1710B_RS21325
Name
bprA
Replicon chromosome II
Genomic location 763556 - 763858 (- strand)

Cross-References

RefSeq YP_335728.1
GI 76817328
Entrez 3692158
GI 76817328
INSDC ABA51275.1
NCBI Locus Tag BURPS1710B_RS21325
NCBI Old Locus Tag BURPS1710b_A0569
RefSeq YP_335728.1
UniParc UPI00005C38AF
UniProtKB Acc Q3JL25
UniProtKB ID Q3JL25_BURP1
UniRef100 UniRef100_A3MCH0
UniRef50 UniRef50_B1Z6M2
UniRef90 UniRef90_A3MCH0

Product

Feature Type CDS
Coding Frame 1
Product Name
HNS-like transcriptional regulator protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 6.47
Kyte-Doolittle Hydrophobicity Value -0.879
Molecular Weight (kDa) 11425.9
Isoelectric Point (pI) 10.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 40 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019831 (366 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS1710b_A0569
Search term: bprA

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592