Burkholderia pseudomallei 668, BURPS668_0019 (gspN)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 668
GCF_000015905.1|latest
Locus Tag
BURPS668_0019
NCBI Locus TagBURPS668_RS00090
Name
gspN
Replicon chromosome I
Genomic location 19449 - 20240 (+ strand)

Cross-References

RefSeq WP_004525775.1
GI 126439999
Entrez 4881868
GI 126439999
INSDC ABN82998.1
NCBI Locus Tag BURPS668_RS00090
NCBI Old Locus Tag BURPS668_0019
RefSeq WP_004525775.1
UniParc UPI00000B02D3
UniProtKB Acc A3N403
UniProtKB ID A3N403_BURP6
UniRef100 UniRef100_Q9ZF75
UniRef50 UniRef50_A1V982
UniRef90 UniRef90_A1V982

Product

Feature Type CDS
Coding Frame 1
Product Name
general secretory pathway protein N
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 6.47
Kyte-Doolittle Hydrophobicity Value 0.098
Molecular Weight (kDa) 27921.9
Isoelectric Point (pI) 11.19

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 23 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000038 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS668_0019
Search term: gspN

Human Homologs

References

Molecular characterization of genetic loci required for secretion of exoproducts in Burkholderia pseudomallei.
DeShazer D, Brett PJ, Burtnick MN, Woods DE
J Bacteriol 1999 Aug;181(15):4661-4
PubMed ID: 10419967
Proteomic analysis of the Burkholderia pseudomallei type II secretome reveals hydrolytic enzymes, novel proteins, and the deubiquitinase TssM.
Burtnick MN, Brett PJ, DeShazer D
Infect Immun 2014 Aug;82(8):3214-26
PubMed ID: 24866793