Burkholderia pseudomallei 668, BURPS668_0008 (gspE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 668
GCF_000015905.1|latest
Locus Tag
BURPS668_0008
NCBI Locus TagBURPS668_RS00040
Name
gspE
Replicon chromosome I
Genomic location 10656 - 12149 (+ strand)

Cross-References

RefSeq WP_004196824.1
GI 126440623
Entrez 4883068
GI 126440623
INSDC ABN83622.1
NCBI Locus Tag BURPS668_RS00040
NCBI Old Locus Tag BURPS668_0008
RefSeq WP_004196824.1
UniParc UPI0000440FA2
UniProtKB Acc A3N3Z2
UniProtKB ID A3N3Z2_BURP6
UniRef100 UniRef100_A0A069B0E3
UniRef50 UniRef50_Q00512
UniRef90 UniRef90_Q63Z29

Product

Feature Type CDS
Coding Frame 1
Product Name
general secretory pathway protein E
Synonyms
Evidence for Translation
Charge (pH 7) -7.96
Kyte-Doolittle Hydrophobicity Value -0.101
Molecular Weight (kDa) 53770.8
Isoelectric Point (pI) 5.93

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 494 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000048 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS668_0008
Search term: gspE

Human Homologs

References

Molecular characterization of genetic loci required for secretion of exoproducts in Burkholderia pseudomallei.
DeShazer D, Brett PJ, Burtnick MN, Woods DE
J Bacteriol 1999 Aug;181(15):4661-4
PubMed ID: 10419967