Burkholderia multivorans ATCC 17616, Bmul_3689 (penA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0046677 | response to antibiotic |
Inferred from Sequence Model
Term mapped from: InterPro:PR00118
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0030655 | beta-lactam antibiotic catabolic process |
Inferred from Sequence Model
Term mapped from: InterPro:PR00118
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0008800 | beta-lactamase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PR00118
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | bmu01501 | beta-Lactam resistance - Burkholderia multivorans ATCC 17616 (JGI) | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bmu01110 | Biosynthesis of secondary metabolites - Burkholderia multivorans ATCC 17616 (JGI) | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00311 | Penicillin and cephalosporin biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bmu00311 | Penicillin and cephalosporin biosynthesis - Burkholderia multivorans ATCC 17616 (JGI) | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bmu01130 | Biosynthesis of antibiotics - Burkholderia multivorans ATCC 17616 (JGI) | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| ProSiteProfiles | PS51318 | Twin arginine translocation (Tat) signal profile. | IPR006311 | Twin-arginine translocation pathway, signal sequence | 1 | 36 | 7.851 |
| PRINTS | PR00118 | Beta-lactamase class A signature | IPR000871 | Beta-lactamase, class-A | 77 | 94 | 4.8E-76 |
| PRINTS | PR00118 | Beta-lactamase class A signature | IPR000871 | Beta-lactamase, class-A | 181 | 206 | 4.8E-76 |
| PRINTS | PR00118 | Beta-lactamase class A signature | IPR000871 | Beta-lactamase, class-A | 119 | 144 | 4.8E-76 |
| PRINTS | PR00118 | Beta-lactamase class A signature | IPR000871 | Beta-lactamase, class-A | 46 | 70 | 4.8E-76 |
| Gene3D | G3DSA:3.40.710.10 | 42 | 302 | 5.4E-86 | |||
| ProSitePatterns | PS00146 | Beta-lactamase class-A active site. | IPR023650 | Beta-lactamase, class-A active site | 79 | 94 | - |
| PRINTS | PR00118 | Beta-lactamase class A signature | IPR000871 | Beta-lactamase, class-A | 234 | 249 | 4.8E-76 |
| SUPERFAMILY | SSF56601 | IPR012338 | Beta-lactamase/transpeptidase-like | 47 | 296 | 4.03E-81 | |
| PRINTS | PR00118 | Beta-lactamase class A signature | IPR000871 | Beta-lactamase, class-A | 155 | 179 | 4.8E-76 |
| PRINTS | PR00118 | Beta-lactamase class A signature | IPR000871 | Beta-lactamase, class-A | 217 | 232 | 4.8E-76 |
| Pfam | PF13354 | Beta-lactamase enzyme family | 67 | 274 | 7.6E-44 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.