Burkholderia mallei ATCC 23344, BMAA1521 (bopA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia mallei ATCC 23344
GCF_000011705.1|latest |
| Locus Tag |
BMAA1521
|
| Name |
bopA
|
| Replicon | chromosome 2 |
| Genomic location | 1650197 - 1651735 (- strand) |
| Comment | This gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus. |
Cross-References
| RefSeq | YP_106112.1 |
| GI | 53716483 |
| NCBI Locus Tag | BMAA1521 |
| RefSeq | YP_106112.1,GeneID |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
type III secretion system effector protein BopA (T3SS-3)
|
| Synonyms |
BopA protein |
| Evidence for Translation | |
| Charge (pH 7) | 24.44 |
| Kyte-Doolittle Hydrophobicity Value | -0.526 |
| Molecular Weight (kDa) | 56799.6 |
| Isoelectric Point (pI) | 10.40 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Virulence Evidence
| Source 1 | |
| Database | BGD |
| Category | T3SS-3 |
| Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
| Host Organism | Mus musculus |
| Notes | |
| Reference | 19369515 |
| Source 2 | |
| Database | VFDB : VF0428 |
| Category | T3SS-3 |
| Evidence |
ECO:0000250
sequence similarity evidence used in manual assertion
|
| Host Organism | |
| Notes | |
| Annotation transferred from | Burkholderia pseudomallei K96243 |
| Reference | 17984080 |
Pathogen Association Analysis
| Results | Analysis not done |
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG019823 (317 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BMAA1521
Search term: bopA
|
Human Homologs
References
|
Stimulation of autophagy suppresses the intracellular survival of Burkholderia pseudomallei in mammalian cell lines.
Cullinane M, Gong L, Li X, Lazar-Adler N, Tra T, Wolvetang E, Prescott M, Boyce JD, Devenish RJ, Adler B
Autophagy 2008 Aug;4(6):744-53
PubMed ID: 18483470
|
|
Coexpression and expression quantitative trait loci analyses of the angiogenesis gene-gene interaction network in prostate cancer.
Lin HY, Cheng CH, Chen DT, Chen YA, Park JY
Transl Cancer Res 2016 Oct;5(Suppl 5):S951-S963
PubMed ID: 28664150
|
|
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
|