Burkholderia xenovorans LB400, Bxe_C0453

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia xenovorans LB400 (Paraburkholderia)
GCF_000013645.1|latest
Locus Tag
Bxe_C0453
NCBI Locus TagBXE_RS38830
Name
Replicon chromosome 3
Genomic location 473442 - 474188 (+ strand)

Cross-References

RefSeq WP_011493613.1
GI 91780500
Entrez 4009967
GI 91780500
NCBI Locus Tag BXE_RS38830
NCBI Old Locus Tag Bxe_C0453
RefSeq WP_011493613.1,GeneID
UniProtKB Acc Q13HT2
UniProtKB ID Q13HT2_BURXL

Product

Feature Type CDS
Coding Frame 1
Product Name
putative type IV secretion system protein VirB8/TraJ
Synonyms
Evidence for Translation
Charge (pH 7) -0.83
Kyte-Doolittle Hydrophobicity Value -0.448
Molecular Weight (kDa) 28205.5
Isoelectric Point (pI) 6.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 59 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006329 (52 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bxe_C0453

Human Homologs

References

Involvement of a plasmid-encoded type IV secretion system in the plant tissue watersoaking phenotype of Burkholderia cenocepacia.
Engledow AS, Medrano EG, Mahenthiralingam E, LiPuma JJ, Gonzalez CF
J Bacteriol 2004 Sep;186(18):6015-24
PubMed ID: 15342570
Two type IV secretion systems with different functions in Burkholderia cenocepacia K56-2.
Zhang R, LiPuma JJ, Gonzalez CF
Microbiology 2009 Dec;155(Pt 12):4005-4013
PubMed ID: 19744991
A type IV secretion system contributes to intracellular survival and replication of Burkholderia cenocepacia.
Sajjan SU, Carmody LA, Gonzalez CF, LiPuma JJ
Infect Immun 2008 Dec;76(12):5447-55
PubMed ID: 18824538