Burkholderia xenovorans LB400, Bxe_C0448

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia xenovorans LB400 (Paraburkholderia)
GCF_000013645.1|latest
Locus Tag
Bxe_C0448
NCBI Locus TagBXE_RS38805
Name
Replicon chromosome 3
Genomic location 468226 - 468561 (+ strand)

Cross-References

RefSeq WP_011493608.1
GI 91780495
Entrez 4009962
GI 91780495
INSDC ABE36352.1
NCBI Locus Tag BXE_RS38805
NCBI Old Locus Tag Bxe_C0448
RefSeq WP_011493608.1,GeneID
UniParc UPI000037E965
UniProtKB Acc Q13HT7
UniProtKB ID Q13HT7_BURXL
UniRef100 UniRef100_Q13HT7
UniRef50 UniRef50_Q13XI6
UniRef90 UniRef90_Q13HT7

Product

Feature Type CDS
Coding Frame 1
Product Name
putative type IV secretion system protein VirB2/TraC
Synonyms
Evidence for Translation
Charge (pH 7) 8.15
Kyte-Doolittle Hydrophobicity Value 0.861
Molecular Weight (kDa) 11756.0
Isoelectric Point (pI) 11.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 13 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG024691 (3 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bxe_C0448

Human Homologs

References

Involvement of a plasmid-encoded type IV secretion system in the plant tissue watersoaking phenotype of Burkholderia cenocepacia.
Engledow AS, Medrano EG, Mahenthiralingam E, LiPuma JJ, Gonzalez CF
J Bacteriol 2004 Sep;186(18):6015-24
PubMed ID: 15342570
Two type IV secretion systems with different functions in Burkholderia cenocepacia K56-2.
Zhang R, LiPuma JJ, Gonzalez CF
Microbiology 2009 Dec;155(Pt 12):4005-4013
PubMed ID: 19744991
A type IV secretion system contributes to intracellular survival and replication of Burkholderia cenocepacia.
Sajjan SU, Carmody LA, Gonzalez CF, LiPuma JJ
Infect Immun 2008 Dec;76(12):5447-55
PubMed ID: 18824538