Burkholderia thailandensis E264 ATCC 700388, BTH_II0689 (bceM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_II0689
NCBI Locus TagBTH_RS03590
Name
bceM
Replicon chromosome II
Genomic location 805233 - 806201 (- strand)
CommentMember of the bce-II gene cluster

Cross-References

RefSeq YP_438888.1
GI 83717405
Entrez 3846581
GI 83717405
INSDC AIP28863.1
NCBI Locus Tag BTH_RS03590
NCBI Old Locus Tag BTH_II0689
RefSeq WP_009895866.1
UniParc UPI0000667793
UniProtKB Acc Q2T7G1
UniProtKB ID Q2T7G1_BURTA
UniRef100 UniRef100_Q2T7G1
UniRef50 UniRef50_Q4K5C5
UniRef90 UniRef90_Q2T7G1

Product

Feature Type CDS
Coding Frame 1
Product Name
GDP-6-deoxy-D-lyxo-4-hexulose reductase BceM
Synonyms GDP-6-deoxy-D-lyxo-4-hexulose reductase
Evidence for Translation
Charge (pH 7) 4.07
Kyte-Doolittle Hydrophobicity Value -0.046
Molecular Weight (kDa) 34762.4
Isoelectric Point (pI) 8.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 636 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000738 (646 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_II0689
Search term: bceM

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863