Burkholderia thailandensis E264 ATCC 700388, BTH_II0683

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004326 tetrahydrofolylpolyglutamate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01499
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.1190.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004326 tetrahydrofolylpolyglutamate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01499
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.1190.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016874 ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53244
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016874 ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53244
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009396 folic acid-containing compound biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01499
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009058 biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.1190.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009396 folic acid-containing compound biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01499
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009058 biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.1190.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00790 Folate biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bte00790 Folate biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc folate polyglutamylation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bte01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.90.190.20 IPR036615 Mur ligase, C-terminal domain superfamily 295 436 1.2E-29
SUPERFAMILY SSF53244 IPR036615 Mur ligase, C-terminal domain superfamily 295 433 2.75E-29
Pfam PF08245 Mur ligase middle domain IPR013221 Mur ligase, central 47 224 8.8E-11
PIRSF PIRSF001563 IPR001645 Folylpolyglutamate synthetase 1 437 4.6E-114
SUPERFAMILY SSF53623 IPR036565 Mur-like, catalytic domain superfamily 6 292 4.27E-90
ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. IPR018109 Folylpolyglutamate synthetase, conserved site 45 68 -
TIGRFAM TIGR01499 folC: bifunctional protein FolC IPR001645 Folylpolyglutamate synthetase 28 428 1.8E-101
Pfam PF02875 Mur ligase family, glutamate ligase domain IPR004101 Mur ligase, C-terminal 294 353 1.7E-5
Gene3D G3DSA:3.40.1190.10 IPR036565 Mur-like, catalytic domain superfamily 1 294 1.2E-90

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.