Strain |
Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest |
Locus Tag |
BTH_II0547
|
NCBI Locus Tag | BTH_RS02855 |
Name |
bceF
|
Replicon | chromosome II |
Genomic location | 649613 - 651832 (+ strand) |
Transposon Mutants | 2 transposon mutants in E264 ATCC 700388 |
Comment | Member of the bce-I gene cluster |
RefSeq | YP_438747.1 |
GI | 83716548 |
Entrez | 3845502 |
GI | 83716548 |
NCBI Locus Tag | BTH_RS02855 |
NCBI Old Locus Tag | BTH_II0547 |
RefSeq | WP_009895611.1 |
UniProtKB Acc | Q2T7V2 |
UniProtKB ID | Q2T7V2_BURTA |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
tyrosine kinase BceF
|
Synonyms |
exopolysaccharide tyrosine-protein kinase |
Evidence for Translation | |
Charge (pH 7) | -0.65 |
Kyte-Doolittle Hydrophobicity Value | -0.068 |
Molecular Weight (kDa) | 79491.4 |
Isoelectric Point (pI) | 6.87 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 463 genera
|
Burkholderia Ortholog Group |
BG004851 (638 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BTH_II0547
Search term: bceF
Search term: tyrosine kinase BceF
|
Functional analysis of Burkholderia cepacia genes bceD and bceF, encoding a phosphotyrosine phosphatase and a tyrosine autokinase, respectively: role in exopolysaccharide biosynthesis and biofilm formation.
Ferreira AS, Leitão JH, Sousa SA, Cosme AM, Sá-Correia I, Moreira LM
Appl Environ Microbiol 2007 Jan;73(2):524-34
PubMed ID: 17114319
|
Comparative transcriptomic analysis of the Burkholderia cepacia tyrosine kinase bceF mutant reveals a role in tolerance to stress, biofilm formation, and virulence.
Ferreira AS, Silva IN, Oliveira VH, Becker JD, Givskov M, Ryan RP, Fernandes F, Moreira LM
Appl Environ Microbiol 2013 May;79(9):3009-20
PubMed ID: 23435894
|
The tyrosine kinase BceF and the phosphotyrosine phosphatase BceD of Burkholderia contaminans are required for efficient invasion and epithelial disruption of a cystic fibrosis lung epithelial cell line.
Ferreira AS, Silva IN, Fernandes F, Pilkington R, Callaghan M, McClean S, Moreira LM
Infect Immun 2015 Feb;83(2):812-21
PubMed ID: 25486990
|
Tyrosine Phosphorylation and Dephosphorylation in Burkholderia cenocepacia Affect Biofilm Formation, Growth under Nutritional Deprivation, and Pathogenicity.
Andrade A, Tavares-Carreón F, Khodai-Kalaki M, Valvano MA
Appl Environ Microbiol 2016 Feb 1;82(3):843-56
PubMed ID: 26590274
|
Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863
|