Burkholderia pseudomallei K96243, BPSS1724

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1724
Name
Replicon chromosome 2
Genomic location 2363001 - 2363510 (+ strand)

Cross-References

RefSeq YP_111730.1
GI 53722745
Entrez 3096701
GI 53722745
INSDC CAH39198.1
NCBI Locus Tag BPSS1724
RefSeq YP_111730.1,GeneID
UniParc UPI000043BDDB
UniProtKB Acc Q63JJ2
UniProtKB ID Q63JJ2_BURPS
UniRef100 UniRef100_A0A097XLS1
UniRef50 UniRef50_A1UZ08
UniRef90 UniRef90_A1UZ08

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724). Found in at least two preparations.
Charge (pH 7) 9.40
Kyte-Doolittle Hydrophobicity Value -0.441
Molecular Weight (kDa) 18064.6
Isoelectric Point (pI) 10.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Periplasmic Class 3
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 11 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003062 (659 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1724

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268