Burkholderia pseudomallei K96243, BPSS1685 (bceQ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1685
Name
bceQ
Replicon chromosome 2
Genomic location 2316694 - 2318160 (- strand)
CommentMember of the bce-II gene cluster
CommentDisruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis

Cross-References

RefSeq YP_111690.1
GI 53722705
Entrez 3096487
GI 53722705
INSDC CAH39158.1
NCBI Locus Tag BPSS1685
RefSeq YP_111690.1,GeneID
UniParc UPI000043BDB3
UniProtKB Acc Q63JN2
UniProtKB ID Q63JN2_BURPS
UniRef100 UniRef100_A0A069BGY9
UniRef50 UniRef50_Q13YU9
UniRef90 UniRef90_Q2T7F6

Product

Feature Type CDS
Coding Frame 1
Product Name
lipopolysaccharide biosynthesis related membrane protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 17.63
Kyte-Doolittle Hydrophobicity Value 0.871
Molecular Weight (kDa) 51986.4
Isoelectric Point (pI) 10.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 56 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003105 (651 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1685
Search term: bceQ

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863