Burkholderia pseudomallei K96243, BPSS1550 (bsaJ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1550
Name
bsaJ
Synonym: sctJ
Replicon chromosome 2
Genomic location 2103636 - 2104583 (+ strand)
CommentThis gene is part of the type III secretion system T3SS-3 (bsa) gene locus.

Cross-References

RefSeq YP_111556.1
GI 53722571
Entrez 3096770
GI 53722571
INSDC CAH39023.1
NCBI Locus Tag BPSS1550
RefSeq YP_111556.1,GeneID
UniParc UPI000043BD30
UniProtKB Acc Q63K16
UniProtKB ID Q63K16_BURPS
UniRef100 UniRef100_A3P717
UniRef50 UniRef50_A3MCE8
UniRef90 UniRef90_A3MCE8

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system inner membrane ring component (T3SS-3)
Product Name Confidence: Class 2
Synonyms Type III secretion system protein
Evidence for Translation
Charge (pH 7) -4.07
Kyte-Doolittle Hydrophobicity Value -0.102
Molecular Weight (kDa) 33165.9
Isoelectric Point (pI) 5.39

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
T3SS
Note: This is based on PSORTb V3.0 secondary localization prediction
Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000314
direct assay evidence used in manual assertion
Host Organism
Notes
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 55 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019860 (321 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1550
Search term: bsaJ

Human Homologs

References

Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152