Burkholderia pseudomallei K96243, BPSL2605 (trxB)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSL2605
Name	trxB
Replicon	chromosome 1
Genomic location	3125983 - 3126945 (+ strand)

Cross-References

RefSeq	YP_109201.1
GI	53720215
Entrez	3092744
GI	53720215
INSDC	CAH36613.1
NCBI Locus Tag	BPSL2605
RefSeq	YP_109201.1,GeneID
UniParc	UPI000043B44D
UniProtKB Acc	Q63RR6
UniProtKB ID	Q63RR6_BURPS
UniRef100	UniRef100_A0A069B7L3
UniRef50	UniRef50_Q9KSS4
UniRef90	UniRef90_Q2SY95

Product

Feature Type	CDS
Coding Frame	1
Product Name	thioredoxin reductase
Synonyms
Evidence for Translation
Charge (pH 7)	-7.23
Kyte-Doolittle Hydrophobicity Value	-0.089
Molecular Weight (kDa)	34137.3
Isoelectric Point (pI)	5.91

Subcellular localization

Individual Mappings	Localization Confidence PMID Extracellular Class 1 quantitative mass spectrometry evidence 25635268 Unknown (This protein may have multiple localization sites) Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 654 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000809 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSL2605 Search term: trxB Search term: thioredoxin reductase

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM Mol Cell Proteomics 2015 Apr;14(4):905-16 PubMed ID: 25635268