Burkholderia pseudomallei K96243, BPSL2518 (pheA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2518
Name
pheA
Replicon chromosome 1
Genomic location 3033465 - 3034547 (- strand)

Cross-References

RefSeq YP_109114.1
GI 53720128
Entrez 3092972
GI 53720128
INSDC CAH36525.1
NCBI Locus Tag BPSL2518
RefSeq YP_109114.1,GeneID
UniParc UPI000043B3F6
UniProtKB Acc Q63S03
UniProtKB ID Q63S03_BURPS
UniRef100 UniRef100_A0A069B9V1
UniRef50 UniRef50_A0A095S0X1
UniRef90 UniRef90_B4EB44

Product

Feature Type CDS
Coding Frame 1
Product Name
chorismate mutase/prephenate dehydratase
Synonyms
Evidence for Translation
Charge (pH 7) -6.95
Kyte-Doolittle Hydrophobicity Value -0.133
Molecular Weight (kDa) 39234.0
Isoelectric Point (pI) 6.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 594 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000885 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2518
Search term: pheA

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268