Burkholderia pseudomallei K96243, BPSL2344 (hutH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00229
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016841 ammonia-lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00488
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004397 histidine ammonia-lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00229
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF48557
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006548 histidine catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00229
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bps00340 Histidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00340 Histidine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-histidine degradation III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc L-histidine degradation II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:1.10.275.10 IPR024083 Fumarase/histidase, N-terminal 1 195 4.1E-63
ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. IPR022313 Phenylalanine/histidine ammonia-lyases, active site 137 153 -
TIGRFAM TIGR01225 hutH: histidine ammonia-lyase IPR005921 Histidine ammonia-lyase 2 498 2.3E-209
Gene3D G3DSA:1.20.200.10 196 502 1.3E-119
CDD cd00332 PAL-HAL IPR001106 Aromatic amino acid lyase 9 450 0.0
Hamap MF_00229 Histidine ammonia-lyase [hutH]. IPR005921 Histidine ammonia-lyase 1 501 44.229
SUPERFAMILY SSF48557 IPR008948 L-Aspartase-like 1 496 9.42E-190
Pfam PF00221 Aromatic amino acid lyase IPR001106 Aromatic amino acid lyase 9 468 2.7E-186

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.