Burkholderia pseudomallei K96243, BPSL2301 (aceE)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0016491 | oxidoreductase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000156
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0003824 | catalytic activity |
Inferred from Sequence Model
Term mapped from: InterPro:SSF52922
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0055114 | oxidation-reduction process |
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000156
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| MetaCyc | thiazole biosynthesis I (facultative anaerobic bacteria) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bps00620 | Pyruvate metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00010 | Glycolysis / Gluconeogenesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bps01130 | Biosynthesis of antibiotics | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00900 | Terpenoid backbone biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bps00020 | Citrate cycle (TCA cycle) | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bps00010 | Glycolysis / Gluconeogenesis | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00620 | Pyruvate metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | thiazole biosynthesis II (aerobic bacteria) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | methylerythritol phosphate pathway II | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00020 | Citrate cycle (TCA cycle) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bps01100 | Metabolic pathways | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bps01200 | Carbon metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bps01110 | Biosynthesis of secondary metabolites | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bps01120 | Microbial metabolism in diverse environments | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00730 | Thiamine metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Pfam | PF00456 | Transketolase, thiamine diphosphate binding domain | IPR005474 | Transketolase, N-terminal | 121 | 303 | 6.8E-8 |
| Pfam | PF17831 | Pyruvate dehydrogenase E1 component middle domain | IPR041621 | Pyruvate dehydrogenase E1 component, middle domain | 482 | 706 | 8.4E-111 |
| TIGRFAM | TIGR00759 | aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type | IPR004660 | Pyruvate dehydrogenase E1 component | 16 | 897 | 0.0 |
| SUPERFAMILY | SSF52518 | IPR029061 | Thiamin diphosphate-binding fold | 479 | 707 | 1.77E-96 | |
| SUPERFAMILY | SSF52518 | IPR029061 | Thiamin diphosphate-binding fold | 66 | 473 | 1.33E-137 | |
| Gene3D | G3DSA:3.40.50.970 | 65 | 477 | 2.7E-133 | |||
| SUPERFAMILY | SSF52922 | IPR009014 | Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II | 712 | 897 | 4.71E-59 | |
| PIRSF | PIRSF000156 | IPR004660 | Pyruvate dehydrogenase E1 component | 6 | 898 | 0.0 | |
| CDD | cd02017 | TPP_E1_EcPDC_like | IPR035807 | Pyruvate dehydrogenase E1 component, N-terminal | 84 | 467 | 0.0 |
| Gene3D | G3DSA:3.40.50.970 | 478 | 712 | 1.0E-108 | |||
| Gene3D | G3DSA:3.40.50.920 | IPR009014 | Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II | 715 | 898 | 5.3E-75 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.