Burkholderia pseudomallei K96243, BPSL2299

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004148 dihydrolipoyl dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01350
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000350
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0045454 cell redox homeostasis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02852
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02852
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0009055 electron transfer activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000350
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050660 flavin adenine dinucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01350
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00076
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00310 Lysine degradation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00020 Citrate cycle (TCA cycle) 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01120 Microbial metabolism in diverse environments 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01200 Carbon metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00020 Citrate cycle (TCA cycle) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00380 Tryptophan metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00640 Propanoate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00010 Glycolysis / Gluconeogenesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00260 Glycine, serine and threonine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc 2-oxoglutarate decarboxylation to succinyl-CoA InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc 2-oxoisovalerate decarboxylation to isobutanoyl-CoA InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00010 Glycolysis / Gluconeogenesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00620 Pyruvate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00280 Valine, leucine and isoleucine degradation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00280 Valine, leucine and isoleucine degradation 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00260 Glycine, serine and threonine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00620 Pyruvate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase IPR023753 FAD/NAD(P)-binding domain 125 445 8.0E-58
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 425 432 1.9E-70
Gene3D G3DSA:3.50.50.60 IPR036188 FAD/NAD(P)-binding domain superfamily 270 391 8.0E-117
Pfam PF00364 Biotin-requiring enzyme IPR000089 Biotin/lipoyl attachment 5 75 9.2E-21
PIRSF PIRSF000350 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I 16 583 5.0E-83
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 258 267 1.9E-70
SUPERFAMILY SSF51905 IPR036188 FAD/NAD(P)-binding domain superfamily 121 454 2.53E-55
Gene3D G3DSA:3.30.390.30 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily 464 584 1.6E-43
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 173 1.9E-70
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 525 540 1.9E-70
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 273 1.8E-40
ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site 159 169 -
Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 464 572 6.7E-32
Gene3D G3DSA:2.40.50.100 2 80 1.5E-21
TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase IPR006258 Dihydrolipoamide dehydrogenase 124 575 1.4E-143
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 381 397 1.8E-40
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 382 396 1.9E-70
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 126 145 1.8E-40
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 293 318 1.9E-70
CDD cd06849 lipoyl_domain 4 76 3.51731E-21
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 125 147 1.9E-70
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 311 1.8E-40
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 460 481 1.9E-70
SUPERFAMILY SSF55424 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily 460 583 3.09E-37
Gene3D G3DSA:3.50.50.60 IPR036188 FAD/NAD(P)-binding domain superfamily 125 450 8.0E-117
SUPERFAMILY SSF51230 IPR011053 Single hybrid motif 2 95 1.31E-23
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 547 567 1.9E-70
ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site 27 56 -
ProSiteProfiles PS50968 Biotinyl/lipoyl domain profile. IPR000089 Biotin/lipoyl attachment 3 77 27.155
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 410 432 1.8E-40

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.