Burkholderia pseudomallei K96243, BPSL2281 (lysS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00152
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004824 lysine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00152
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00152
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004824 lysine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01336
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006430 lysyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01336
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00152
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006430 lysyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00970 Aminoacyl-tRNA biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00970 Aminoacyl-tRNA biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00982 Lysyl-tRNA synthetase signature IPR018149 Lysyl-tRNA synthetase, class II, C-terminal 214 230 2.2E-38
ProSiteProfiles PS50862 Aminoacyl-transfer RNA synthetases class-II family profile. IPR006195 Aminoacyl-tRNA synthetase, class II 183 502 28.154
TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase IPR002313 Lysine-tRNA ligase, class II 15 506 7.7E-198
Gene3D G3DSA:2.40.50.140 15 153 1.0E-40
Pfam PF00152 tRNA synthetases class II (D, K and N) IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) 161 504 9.5E-83
Pfam PF01336 OB-fold nucleic acid binding domain IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 68 145 4.1E-14
PRINTS PR00982 Lysyl-tRNA synthetase signature IPR018149 Lysyl-tRNA synthetase, class II, C-terminal 198 208 2.2E-38
PRINTS PR00982 Lysyl-tRNA synthetase signature IPR018149 Lysyl-tRNA synthetase, class II, C-terminal 243 256 2.2E-38
PRINTS PR00982 Lysyl-tRNA synthetase signature IPR018149 Lysyl-tRNA synthetase, class II, C-terminal 261 278 2.2E-38
Hamap MF_00252 Lysine--tRNA ligase [lysS]. IPR002313 Lysine-tRNA ligase, class II 21 507 43.93
SUPERFAMILY SSF50249 IPR012340 Nucleic acid-binding, OB-fold 14 154 4.29E-41
CDD cd00775 LysRS_core IPR018149 Lysyl-tRNA synthetase, class II, C-terminal 177 505 0.0
CDD cd04322 LysRS_N 67 173 1.21421E-56
Gene3D G3DSA:3.30.930.10 161 505 6.6E-133
PRINTS PR00982 Lysyl-tRNA synthetase signature IPR018149 Lysyl-tRNA synthetase, class II, C-terminal 389 405 2.2E-38
SUPERFAMILY SSF55681 161 505 4.42E-116

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.