Burkholderia pseudomallei K96243, BPSL2258 (dapA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.20.20.70
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016829 lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00146
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00418
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009089 lysine biosynthetic process via diaminopimelate
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00418
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc L-lysine biosynthesis VI InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-lysine biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-lysine biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00261 Monobactam biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01120 Microbial metabolism in diverse environments 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00300 Lysine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01230 Biosynthesis of amino acids 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00300 Lysine biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA 10 296 66.873
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 137 154 1.0E-33
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 80 98 1.0E-33
Pfam PF00701 Dihydrodipicolinate synthetase family IPR002220 DapA-like 11 295 6.3E-103
SUPERFAMILY SSF51569 11 298 3.04E-106
ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. IPR020625 Schiff base-forming aldolase, active site 142 172 -
CDD cd00950 DHDPS IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA 11 294 4.5161E-158
TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA 14 296 4.0E-111
PIRSF PIRSF001365 IPR002220 DapA-like 6 300 2.1E-97
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 44 65 1.0E-33
Gene3D G3DSA:3.20.20.70 IPR013785 Aldolase-type TIM barrel 10 300 4.9E-112
PRINTS PR00146 Dihydrodipicolinate synthase signature IPR002220 DapA-like 112 128 1.0E-33
SMART SM01130 IPR002220 DapA-like 10 298 5.2E-146

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.