Burkholderia pseudomallei K96243, BPSL2155 (uppS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2155
Name
uppS
Replicon chromosome 1
Genomic location 2586030 - 2586812 (- strand)

Cross-References

RefSeq YP_108750.1
GI 53719764
Entrez 3093554
GI 53719764
INSDC CAH36157.1
NCBI Locus Tag BPSL2155
RefSeq YP_108750.1,GeneID
UniParc UPI000043B28E
UniProtKB Acc Q63T16
UniProtKB ID Q63T16_BURPS
UniRef100 UniRef100_A0A069B6A6
UniRef50 UniRef50_Q9HXY2
UniRef90 UniRef90_A1V565

Product

Feature Type CDS
Coding Frame 1
Product Name
undecaprenyl pyrophosphate synthetase
Synonyms
Evidence for Translation
Charge (pH 7) 2.15
Kyte-Doolittle Hydrophobicity Value -0.329
Molecular Weight (kDa) 29378.9
Isoelectric Point (pI) 8.23

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 658 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001905 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2155
Search term: uppS

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268