Burkholderia pseudomallei K96243, BPSL2098 (ispF)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0016114	terpenoid biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00554	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0016114	terpenoid biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00554	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008685	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00554	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008685	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00554	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	bps00900	Terpenoid backbone biosynthesis	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
MetaCyc		methylerythritol phosphate pathway II	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	bps01110	Biosynthesis of secondary metabolites	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bps01130	Biosynthesis of antibiotics	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG (InterPro)	00900	Terpenoid backbone biosynthesis	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	bps01100	Metabolic pathways	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Gene3D	G3DSA:3.30.1330.50		IPR036571	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily	1	162	1.0E-70
TIGRFAM	TIGR00151	ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	IPR003526	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	4	157	4.6E-68
SUPERFAMILY	SSF69765		IPR036571	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily	1	158	1.96E-66
Pfam	PF02542	YgbB family	IPR003526	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	3	156	3.5E-65
ProSitePatterns	PS01350	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature.	IPR020555	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site	37	52	-
Hamap	MF_00107	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF].	IPR003526	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	3	158	37.111
CDD	cd00554	MECDP_synthase	IPR003526	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	4	156	6.13299E-91

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.