Burkholderia pseudomallei K96243, BPSL2003

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2003
Name
Replicon chromosome 1
Genomic location 2388211 - 2388546 (+ strand)

Cross-References

RefSeq YP_108601.1
GI 53719615
Entrez 3094867
GI 53719615
INSDC CAH36002.1
NCBI Locus Tag BPSL2003
RefSeq YP_108601.1,GeneID
UniParc UPI000043B1FA
UniProtKB Acc Q63TG5
UniProtKB ID Y2003_BURPS
UniRef100 UniRef100_A3N8L4
UniRef50 UniRef50_Q2SV78
UniRef90 UniRef90_Q2SV78

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724).
Charge (pH 7) 0.92
Kyte-Doolittle Hydrophobicity Value 0.094
Molecular Weight (kDa) 11952.5
Isoelectric Point (pI) 8.19

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Unknown Class 3
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 238 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004003 (633 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2003

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268