Burkholderia pseudomallei K96243, BPSL1985

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1985
Name
Replicon chromosome 1
Genomic location 2367951 - 2368679 (- strand)

Cross-References

RefSeq YP_108583.1
GI 53719597
Entrez 3094683
GI 53719597
INSDC CAH35984.1
NCBI Locus Tag BPSL1985
RefSeq YP_108583.1,GeneID
UniParc UPI000043B1E8
UniProtKB Acc Q63TI3
UniProtKB ID Q63TI3_BURPS
UniRef100 UniRef100_A1V3I3
UniRef50 UniRef50_A1V3I3
UniRef90 UniRef90_A1V3I3

Product

Feature Type CDS
Coding Frame 1
Product Name
two component system response regulator
Synonyms
Evidence for Translation
Charge (pH 7) 0.17
Kyte-Doolittle Hydrophobicity Value -0.307
Molecular Weight (kDa) 27586.3
Isoelectric Point (pI) 7.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 616 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001264 (650 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1985

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268