Burkholderia pseudomallei K96243, BPSL1980 (valS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1980
Name
valS
Replicon chromosome 1
Genomic location 2359584 - 2362451 (+ strand)

Cross-References

RefSeq YP_108578.1
GI 53719592
Entrez 3094083
GI 53719592
INSDC CAH35979.1
NCBI Locus Tag BPSL1980
RefSeq YP_108578.1,GeneID
UniParc UPI000043B1E3
UniProtKB Acc Q63TI8
UniProtKB ID SYV_BURPS
UniRef100 UniRef100_Q63TI8
UniRef50 UniRef50_Q63TI8
UniRef90 UniRef90_Q63TI8

Product

Feature Type CDS
Coding Frame 1
Product Name
valyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -13.76
Kyte-Doolittle Hydrophobicity Value -0.261
Molecular Weight (kDa) 106725.0
Isoelectric Point (pI) 5.98

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 668 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001268 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1980
Search term: valS

Human Homologs

Ensembl 97, assembly GRCh38.p12
valyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:12651]
E-value: 1.1e-194
Percent Identity: 39.9
Ensembl 97, assembly GRCh38.p12
valyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:12651]
E-value: 1.1e-194
Percent Identity: 39.9
Ensembl 97, assembly GRCh38.p12
valyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:12651]
E-value: 1.1e-194
Percent Identity: 39.9
Ensembl 97, assembly GRCh38.p12
valyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:12651]
E-value: 1.1e-194
Percent Identity: 39.9
Ensembl 97, assembly GRCh38.p12
valyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:12651]
E-value: 1.1e-194
Percent Identity: 39.9
Ensembl 97, assembly GRCh38.p12
valyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:12651]
E-value: 1.1e-194
Percent Identity: 39.9

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268