Burkholderia pseudomallei K96243, BPSL1922

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1922
Name
Replicon chromosome 1
Genomic location 2292339 - 2293706 (- strand)

Cross-References

RefSeq YP_108522.1
GI 53719536
Entrez 3092191
GI 53719536
INSDC CAH35922.1
NCBI Locus Tag BPSL1922
RefSeq YP_108522.1,GeneID
UniParc UPI000043B1AD
UniProtKB Acc Q63TP4
UniProtKB ID Q63TP4_BURPS
UniRef100 UniRef100_Q63TP4
UniRef50 UniRef50_A1V3N8
UniRef90 UniRef90_A1V3N8

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (44.1 kDa, pI 4.16, PMID:21960737)
Charge (pH 7) -42.85
Kyte-Doolittle Hydrophobicity Value -0.581
Molecular Weight (kDa) 47754.3
Isoelectric Point (pI) 4.23

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 414 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001324 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1922

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268