Burkholderia pseudomallei K96243, BPSL1514 (hisS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006427 histidyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00127
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF001549
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004821 histidine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00127
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00127
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00970 Aminoacyl-tRNA biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00970 Aminoacyl-tRNA biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF55681 14 328 1.4E-98
PIRSF PIRSF001549 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit 7 437 2.1E-117
ProSiteProfiles PS50862 Aminoacyl-transfer RNA synthetases class-II family profile. IPR006195 Aminoacyl-tRNA synthetase, class II 1 341 21.47
Pfam PF13393 Histidyl-tRNA synthetase IPR041715 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain 16 318 2.8E-50
Pfam PF03129 Anticodon binding domain IPR004154 Anticodon-binding 336 434 7.0E-10
Hamap MF_00127 Histidine--tRNA ligase [hisS]. IPR015807 Histidine-tRNA ligase 9 435 32.346
CDD cd00773 HisRS-like_core IPR041715 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain 24 323 3.59765E-97
SUPERFAMILY SSF52954 333 435 3.32E-21
CDD cd00859 HisRS_anticodon IPR033656 Histidyl-anticodon-binding 333 434 8.12742E-26
TIGRFAM TIGR00442 hisS: histidine--tRNA ligase IPR015807 Histidine-tRNA ligase 14 412 1.4E-151
Gene3D G3DSA:3.30.930.10 8 331 1.2E-132
Gene3D G3DSA:3.40.50.800 IPR036621 Anticodon-binding domain superfamily 332 432 5.8E-29

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.