Burkholderia pseudomallei K96243, BPSL0906 (ileS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000049 tRNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd07960
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0002161 aminoacyl-tRNA editing activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.740.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006428 isoleucyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00392
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00133
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00133
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00133
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00133
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004822 isoleucine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00392
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bps00970 Aminoacyl-tRNA biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00970 Aminoacyl-tRNA biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd07960 Anticodon_Ia_Ile_BEm IPR033708 Isoleucyl tRNA synthetase type 1, anticodon-binding domain 660 837 2.06518E-80
SUPERFAMILY SSF50677 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 211 416 1.99E-47
SUPERFAMILY SSF47323 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding 672 935 2.62E-71
PRINTS PR00984 Isoleucyl-tRNA synthetase signature IPR002301 Isoleucine-tRNA ligase 581 590 4.7E-31
Gene3D G3DSA:1.10.730.20 660 936 3.6E-86
Pfam PF06827 Zinc finger found in FPG and IleRS IPR010663 Zinc finger, FPG/IleRS-type 907 932 1.5E-7
ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site 66 77 -
PRINTS PR00984 Isoleucyl-tRNA synthetase signature IPR002301 Isoleucine-tRNA ligase 59 70 4.7E-31
Pfam PF00133 tRNA synthetases class I (I, L, M and V) IPR002300 Aminoacyl-tRNA synthetase, class Ia 35 660 5.2E-187
Gene3D G3DSA:3.90.740.10 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 200 421 7.6E-217
TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase IPR002301 Isoleucine-tRNA ligase 23 859 1.3E-259
SUPERFAMILY SSF52374 16 668 4.93E-126
PRINTS PR00984 Isoleucyl-tRNA synthetase signature IPR002301 Isoleucine-tRNA ligase 545 558 4.7E-31
PRINTS PR00984 Isoleucyl-tRNA synthetase signature IPR002301 Isoleucine-tRNA ligase 244 267 4.7E-31
Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. IPR023585 Isoleucine-tRNA ligase, type 1 10 936 20.237
CDD cd00818 IleRS_core 57 657 1.02691E-93
PRINTS PR00984 Isoleucyl-tRNA synthetase signature IPR002301 Isoleucine-tRNA ligase 414 429 4.7E-31
Pfam PF08264 Anticodon-binding domain of tRNA IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding 705 858 3.8E-25
Gene3D G3DSA:3.40.50.620 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 33 649 7.6E-217

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.