Burkholderia pseudomallei K96243, BPSL0903 (dut)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00116
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0046081 dUTP catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00116
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004170 dUTP diphosphatase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00116
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006226 dUMP biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00116
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00240 Pyrimidine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00983 Drug metabolism - other enzymes InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00240 Pyrimidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
TIGRFAM TIGR00576 dut: dUTP diphosphatase IPR008181 Deoxyuridine triphosphate nucleotidohydrolase 9 147 1.0E-47
CDD cd07557 trimeric_dUTPase IPR033704 dUTPase, trimeric 25 118 7.06596E-30
SUPERFAMILY SSF51283 IPR036157 dUTPase-like superfamily 12 147 4.58E-51
Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. IPR008181 Deoxyuridine triphosphate nucleotidohydrolase 5 147 33.641
Gene3D G3DSA:2.70.40.10 IPR036157 dUTPase-like superfamily 1 147 5.5E-51
Pfam PF00692 dUTPase IPR029054 dUTPase-like 16 146 1.5E-37

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.