Burkholderia pseudomallei K96243, BPSL0896 (icd)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00470
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01329
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00470
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01329
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004450 isocitrate dehydrogenase (NADP+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00183
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006099 tricarboxylic acid cycle
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00183
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bps00480 Glutathione metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc ethylene biosynthesis V (engineered) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc methylaspartate cycle InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01120 Microbial metabolism in diverse environments 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01200 Carbon metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01230 Biosynthesis of amino acids 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc TCA cycle VII (acetate-producers) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-glutamine biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00020 Citrate cycle (TCA cycle) 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01210 2-Oxocarboxylic acid metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc NAD/NADP-NADH/NADPH cytosolic interconversion (yeast) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc partial TCA cycle (obligate autotrophs) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00480 Glutathione metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00720 Carbon fixation pathways in prokaryotes InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00020 Citrate cycle (TCA cycle) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM01329 IPR024084 Isopropylmalate dehydrogenase-like domain 30 414 8.7E-176
Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase IPR024084 Isopropylmalate dehydrogenase-like domain 31 412 5.5E-115
Coils Coil 415 419 -
TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic 3 419 1.3E-222
SUPERFAMILY SSF53659 4 418 8.64E-146
ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site 305 324 -
Gene3D G3DSA:3.40.718.10 1 419 3.0E-194

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.