Burkholderia pseudomallei K96243, BPSL0875 (adk)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0875
Name
adk
Replicon chromosome 1
Genomic location 1015408 - 1016070 (- strand)

Cross-References

RefSeq YP_107500.1
GI 53718514
Entrez 3091823
GI 53718514
INSDC CAH34867.1
NCBI Locus Tag BPSL0875
RefSeq YP_107500.1,GeneID
UniParc UPI000043ADB5
UniProtKB Acc Q63WL6
UniProtKB ID KAD_BURPS
UniRef100 UniRef100_A3MN48
UniRef50 UniRef50_C5BD16
UniRef90 UniRef90_Q2T0K4

Product

Feature Type CDS
Coding Frame 1
Product Name
adenylate kinase
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (24.2 kDa, pI 4.88, PMID:21960737)
Charge (pH 7) 1.45
Kyte-Doolittle Hydrophobicity Value -0.378
Molecular Weight (kDa) 24169.5
Isoelectric Point (pI) 8.38

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3GMT TRANSFERASE 03/15/09 Crystal structure of adenylate kinase from burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI 1710B 2.1 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 631 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002411 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0875
Search term: adk
Search term: adenylate kinase

Human Homologs

Ensembl 97, assembly GRCh38.p12
adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362]
E-value: 1.1e-49
Percent Identity: 48.5
Ensembl 97, assembly GRCh38.p12
adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362]
E-value: 1.1e-49
Percent Identity: 48.5
Ensembl 97, assembly GRCh38.p12
adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362]
E-value: 1.1e-49
Percent Identity: 48.5

References

No references are associated with this feature.