Burkholderia pseudomallei K96243, BPSL0803

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0803
Name
Replicon chromosome 1
Genomic location 931480 - 932619 (- strand)

Cross-References

RefSeq YP_107428.1
GI 53718442
Entrez 3094179
GI 53718442
INSDC CAH34795.1
NCBI Locus Tag BPSL0803
RefSeq YP_107428.1,GeneID
UniParc UPI000043AD6E
UniProtKB Acc Q63WT8
UniProtKB ID Q63WT8_BURPS
UniRef100 UniRef100_I1WM41
UniRef50 UniRef50_E5AKX3
UniRef90 UniRef90_Q2T0S3

Product

Feature Type CDS
Coding Frame 1
Product Name
acylhydrolase
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724). Found in at least two preparations.
Charge (pH 7) -1.91
Kyte-Doolittle Hydrophobicity Value 0.083
Molecular Weight (kDa) 38776.1
Isoelectric Point (pI) 6.34

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Extracellular Class 3
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 63 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002480 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0803
Search term: acylhydrolase

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268